Cardiovascular risk factors for mild cognitive impairment

Citation
Cardiovascular risk factors for mild cognitive impairment

Material Information

Title:
Cardiovascular risk factors for mild cognitive impairment
Creator:
Malek-Ahmadi, Michael
Place of Publication:
[Tampa, Fla]
Publisher:
University of South Florida
Publication Date:
Language:
English

Subjects

Subjects / Keywords:
Hba1c
Diabetes
Cholesterol
Hypertension
Homocysteine
Dissertations, Academic -- Epidemiology and Biostatistics -- Masters -- USF ( lcsh )
Genre:
non-fiction ( marcgt )

Notes

Abstract:
ABSTRACT: The relationship between cardiovascular conditions and the presence of Alzheimer's disease (AD) has been well-documented in a number of recent studies. Generally, the presence of cardiovascular conditions such as high total cholesterol and hypertension have been shown to significantly increase the risk for the development of AD. Given the results of these studies, it is possible that these same risk factors might also increase the risk of developing mild cognitive impairment (MCI). An analysis of 216 subjects (119 cognitively normal (CN), 77 aMCI, 20 naMCI) found that after adjusting for age, education, ethnicity, and gender, only hemoglobin A1c (HbA1c) showed a significant effect for aMCI [OR = 1.75 (1.02, 2.99) p=0.04]. Age and education also showed significant effects that were consistent with previous studies. Given recent studies linking Type 2 diabetes with AD, this finding appears to strengthen the link between diabetes-related disease processes and aMCI/AD disease processes.
Thesis:
Thesis (M.S.P.H.)--University of South Florida, 2009.
Bibliography:
Includes bibliographical references.
System Details:
Mode of access: World Wide Web.
System Details:
System requirements: World Wide Web browser and PDF reader.
General Note:
Title from PDF of title page.
General Note:
Document formatted into pages; contains 34 pages.
Statement of Responsibility:
by Michael Malek-Ahmadi.

Record Information

Source Institution:
University of South Florida Library
Holding Location:
University of South Florida
Rights Management:
All applicable rights reserved by the source institution and holding location.
Resource Identifier:
002029075 ( ALEPH )
436864433 ( OCLC )
E14-SFE0002872 ( USFLDC DOI )
e14.2872 ( USFLDC Handle )

Postcard Information

Format:
Book

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This item has the following downloads:


Full Text
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Cardiovascular risk factors for mild cognitive impairment
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ABSTRACT: The relationship between cardiovascular conditions and the presence of Alzheimer's disease (AD) has been well-documented in a number of recent studies. Generally, the presence of cardiovascular conditions such as high total cholesterol and hypertension have been shown to significantly increase the risk for the development of AD. Given the results of these studies, it is possible that these same risk factors might also increase the risk of developing mild cognitive impairment (MCI). An analysis of 216 subjects (119 cognitively normal (CN), 77 aMCI, 20 naMCI) found that after adjusting for age, education, ethnicity, and gender, only hemoglobin A1c (HbA1c) showed a significant effect for aMCI [OR = 1.75 (1.02, 2.99) p=0.04]. Age and education also showed significant effects that were consistent with previous studies. Given recent studies linking Type 2 diabetes with AD, this finding appears to strengthen the link between diabetes-related disease processes and aMCI/AD disease processes.
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Mode of access: World Wide Web.
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Cholesterol
Hypertension
Homocysteine
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