ORF8-related genetic evidence for Chinese horseshoe bats as the source of human Severe Acute Respiratory Syndrome coronavirus

Citation

Material Information

Title:
ORF8-related genetic evidence for Chinese horseshoe bats as the source of human Severe Acute Respiratory Syndrome coronavirus
Series Title:
Journal of infectious diseases
Creator:
Wu, Zhiqiang
Yang, Li
Ren, Xianwen
Zhang, Junpeng
Yang, Fan
Zhang, Shuyi
Jin, Qi
Publisher:
Oxford University Press
Publication Date:
Physical Description:
1 online resource

Subjects

Subjects / Keywords:
Coronaviruses ( lcsh )
SARS (Disease) ( lcsh )
Horseshoe bats ( lcsh )
Genre:
serial ( sobekcm )
Location:
Asia -- China

Notes

Abstract:
Several lineage B betacoronaviruses termed severe acute respiratory syndrome (SARS)–like CoVs (SL-CoVs) were identified from Rhinolophus bats in China. These viruses are characterized by a set of unique accessory open reading frames (ORFs) that are located between the M and N genes. Among unique accessory ORFs, ORF8 is most hypervariable. In this study, the ORF8s of all SL-CoVs were classified into 3 types, and, for the first time, it was found that very few SL-CoVs from Rhinolophus sinicus have ORF8s that are identical to that of human SARS-CoV. This finding provides new genetic evidence for Chinese horseshoe bats as the source of human SARS-CoV.
Original Version:
Volume 213, Issue 4

Record Information

Source Institution:
University of South Florida
Holding Location:
University of South Florida
Rights Management:
All applicable rights reserved by the source institution and holding location.
Resource Identifier:
K26-05433 ( USFLDC DOI )
k26.5433 ( USFLDC Handle )

USFLDC Membership

Aggregations:
University of South Florida
Karst Information Portal

Postcard Information

Format:
serial

printinsert_linkshareget_appmore_horiz

Download Options [CUSTOM IMAGE]

close
No images are available for this item.
Cite this item close

APA

Cras ut cursus ante, a fringilla nunc. Mauris lorem nunc, cursus sit amet enim ac, vehicula vestibulum mi. Mauris viverra nisl vel enim faucibus porta. Praesent sit amet ornare diam, non finibus nulla.

MLA

Cras efficitur magna et sapien varius, luctus ullamcorper dolor convallis. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Fusce sit amet justo ut erat laoreet congue sed a ante.

CHICAGO

Phasellus ornare in augue eu imperdiet. Donec malesuada sapien ante, at vehicula orci tempor molestie. Proin vitae urna elit. Pellentesque vitae nisi et diam euismod malesuada aliquet non erat.

WIKIPEDIA

Nunc fringilla dolor ut dictum placerat. Proin ac neque rutrum, consectetur ligula id, laoreet ligula. Nulla lorem massa, consectetur vitae consequat in, lobortis at dolor. Nunc sed leo odio.