Extreme lifespan of the human fish (Proteus anguinus): a challenge for ageing mechanisms

Citation

Material Information

Title:
Extreme lifespan of the human fish (Proteus anguinus): a challenge for ageing mechanisms
Series Title:
Biology Letters
Creator:
Voituron, Yann
de Fraipont, Michelle
Issartel, Julien
Guillaume, Olivier
Clobert, Jean
Publisher:
The Royal Society Publishing
Publication Date:
Language:
English

Subjects

Subjects / Keywords:
Subterranean Environment ( local )
Metabolism ( local )
Longevity ( local )
Amphibian ( local )
Genre:
serial ( sobekcm )

Notes

Abstract:
Theories of extreme lifespan evolution in vertebrates commonly implicate large size and predator-free environments together with physiological characteristics like low metabolism and high protection against oxidative damages. Here, we show that the ‘human fish’ (olm, Proteus anguinus), a small cave salamander (weighing 15–20 g), has evolved an extreme life-history strategy with a predicted maximum lifespan of over 100 years, an adult average lifespan of 68.5 years, an age at sexual maturity of 15.6 years and lays, on average, 35 eggs every 12.5 years. Surprisingly, neither its basal metabolism nor antioxidant activities explain why this animal sits as an outlier in the amphibian size/longevity relationship. This species thus raises questions regarding ageing processes and constitutes a promising model for discovering mechanisms preventing senescence in vertebrates.
Original Version:
Biology Letters, Vol. 7, no. 1 (2010-07-21).

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Source Institution:
University of South Florida Library
Holding Location:
University of South Florida
Rights Management:
This object is protected by copyright, and is made available here for research and educational purposes. Permission to reuse, publish, or reproduce the object beyond the bounds of Fair Use or other exemptions to copyright law must be obtained from the copyright holder.

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