An early modern human from Romania with a recent Neanderthal ancestor

Citation

Material Information

Title:
An early modern human from Romania with a recent Neanderthal ancestor
Series Title:
Nature
Creator:
Fu, Qiaomei
Hajdinjak, Mateja
Teodora Moldovan, Oana
Constantin, Silviu
Mallick, Swapan
Skoglund, Pontus
Patterson, Nick
Rohland, Nadin
Lazaridis, Iosif
Nickel, Birgit
Viola, Bence
Prüfer, Kay
Meyer, Matthias
Kelso, Janet
Reich, David
Pääbo, Svante
Publication Date:
Language:
English

Subjects

Subjects / Keywords:
Modern Human ( local )
Romania ( local )
Human DNA ( local )
Genre:
serial ( sobekcm )

Notes

Abstract:
Neanderthals are thought to have disappeared in Europe approximately 39,000–41,000 years ago but they have contributed 1–3% of the DNA of present-day people in Eurasia1. Here we analyse DNA from a 37,000–42,000-year-old2 modern human from Peştera cu Oase, Romania. Although the specimen contains small amounts of human DNA, we use an enrichment strategy to isolate sites that are informative about its relationship to Neanderthals and present-day humans. We find that on the order of 6–9% of the genome of the Oase individual is derived from Neanderthals, more than any other modern human sequenced to date. Three chromosomal segments of Neanderthal ancestry are over 50 centimorgans in size, indicating that this individual had a Neanderthal ancestor as recently as four to six generations back. However, the Oase individual does not share more alleles with later Europeans than with East Asians, suggesting that the Oase population did not contribute substantially to later humans in Europe.
Original Version:
Nature, Vol. 524 (2015-06-22).

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University of South Florida Library
Holding Location:
University of South Florida
Rights Management:
This object is protected by copyright, and is made available here for research and educational purposes. Permission to reuse, publish, or reproduce the object beyond the bounds of Fair Use or other exemptions to copyright law must be obtained from the copyright holder.

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